Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

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4,561 – 4,575 of 60,538 results

4,561

Cayman Chemical Lixivaptan, Purity: ≥97%, CAS: 168079-32-1, 10 mg

A nonpeptide antagonist of vasopressin V2 receptors (Ki = 2.3 nM)

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4,562

Cayman Chemical MK6-83, Purity: ≥98%, CAS: 1062271-24-2, 5 mg

A TRPML1 activator (EC50s = 110, 100, and 1,230 nM in wild type, F465L, and F408Δ-expressing fibroblasts, respectively); improves zinc trafficking out of lysosomes

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4,563

Advanced Chemblocks Inc EXATECAN MESYLATE 25G

Exatecan Mesylate 25GCAS #:169869-90-3Purity:98%

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4,564

Medchemexpress LLC (((9H-fluoren-9-yl)methoxy)carbonyl)-D-lysine | 110990-08-4 | MFCD04113545 | 99.5% | 368.43 g/mol | C21H24N2O4 | 1 G

(((9H-fluoren-9-yl)methoxy)carbonyl)-D-lysine is an Fmoc-protected D-lysine amino acid derivative used primarily as a building block in solid-phase peptide synthesis and related peptide chemistry applications. It is provided as a high-purity, crystalline compound suitable for coupling reactions and standard peptide synthesis workflows.

Fmoc-protected D-lysine suitable for peptide synthesis.
High-purity material for reliable coupling and characterization.
Formula: C21H24N2O4 and molecular weight 368.43 g/mol.
CAS 110990-08-4 for unambiguous identification.
Available in small laboratory quantities for research use.
Store protected from light at refrigerated temperatures; follow solvent storage guidance for long-term stability.

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4,565

Cayman Chemical DOAM, Purity: ≥98%, CAS: 63779-90-8, 5 mg

An amphetamine that may act as an antagonist of the 5-HT2 receptor

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4,566

Medchemexpress LLC BMS-707035 50 mg

BMS-707035 50MG

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4,567

Medchemexpress LLC Boc-N-gamma-trityl-D-asparagin | 210529-01-4 | 98.6% | 474.55 g/mol | C28H30N2O5 | 10 G

Boc-N-gamma-trityl-D-asparagin is a Boc- and trityl-protected D-asparagine derivative used as a protected amino acid building block in peptide synthesis and organic synthetic workflows. It provides Boc protection on the amino group and trityl protection on the side-chain amide, enabling orthogonal deprotection strategies and protecting asparagine residues during multi-step syntheses.

Provides Boc protection on the α-amino group and trityl protection on the side-chain amide.
Suitable for peptide synthesis and orthogonal protection strategies.
High purity for research applications.
Available in gram-scale packs for laboratory use.

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4,568

Cayman Chemical Fulacimstat, Purity: ≥98%, CAS: 1488354-15-9, 5 mg

A chymase inhibitor (IC50s = 4 and 3 nM for the human and hamster enzyme, respectively); reduces isoprenaline-induced cardiac fibrosis in hamsters at 1, 3, and 10 mg/kg; inhibits decreases in left ventricular ejection fraction and increases in left ventricular end-systolic volume, decreases in plasma levels of nt-proBNP, TGF-β1, and TNF-α, as well as the levels of interstitial fibrosis and the cross-sectional area of myocytes, in a coronary microembolism-induced canine model of heart failure at 2 and 5 mg/kg per day

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4,569

Cayman Chemical GR127935 (hydrochloride), Purity: ≥98%, CAS: 148642-42-6, 5 mg

A 5-HT1B and 5-HT1D receptor antagonist (IC50s = 3.16, 1.26, and 0.13 nM, respectively); selective for the 5-HT1B and 5-HT1D receptors over other 5-HT receptors (IC50s = 39.81->10,000 nM in radioligand binding assays); enhances memory consolidation in an autoshaping learning task in rats when administered post-training at 10 mg/kg; has been used to elucidate the 5-HT receptor subtypes involved in the anti-inflammatory activity of sumatriptan

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4,570

Medchemexpress LLC Gne-493 | 1033735-94-2 | MFCD18251526 | 99.8% | 372.44 g/mol | C17H20N6O2S | 1 ML

GNE-493 is a potent, selective, orally available small-molecule inhibitor of class I PI3K isoforms and mTOR, with demonstrated biochemical potency and cellular antiproliferative activity. It is supplied as a solid or as ready-to-use DMSO solutions (for example, 10 mM, 1 mL).

Dual pan-PI3K and mTOR inhibition with low-nanomolar IC50s.
Biochemical IC50s: PI3Kα 3.4 nM; PI3Kβ 12 nM; PI3Kδ 16 nM; PI3Kγ 16 nM; mTOR 30 nM.
Cellular antiproliferative activity (PC-3 IC50 0.33 μM).
High purity and defined physicochemical profile (MW 372.44; formula C17H20N6O2S).
Available as solution in DMSO or as a solid for custom formulation.

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4,571

Medchemexpress LLC Siais164018 hydrochloride | 00-00-0 | 98.1% | C43H49Cl2N10O7P | 10MG

SIAIS164018 hydrochloride is a PROTAC-based degrader that targets ALK and EGFR, demonstrating potent cellular activity to inhibit cancer cell migration, induce G1 cell cycle arrest, and promote apoptosis. Reported activity includes low-nanomolar potency in relevant assays. Supplied as a purified research compound for biochemical and cellular studies.

Potent ALK and EGFR degradation in cellular assays.
Inhibits cancer cell migration and invasion.
Induces G1 cell cycle arrest and apoptosis.
High reported purity and defined molecular properties.
Supplied in small-mass research quantities for in vitro studies.

Pricing & Availability

4,572

Medchemexpress LLC Rabdosiin ((+)-Rabdosiin) | 263397-69-9 | 10 MG

Rabdosiin ((+)-Rabdosiin) is a Caffeic acid tetramer isolated from *Macrotomia euchroma*. It appears as an off-white to yellow solid.

Intended for research use only.
Molecular weight of 718.61.
Molecular formula C36H30O16.

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4,573

Medchemexpress LLC GUANOSINE-5 -TRIPHOS 500 mg

GUANOSINE-5 -TRIPHOS 500MG

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4,574

Apexbio Technology LLC SR-18292-5MG

SR-18292 (CAS No 2095432-55-4) is a novel compound in the category of small molecule inhibitors originating from advanced synthetic chemistry processes It primarily targets cellular signaling pathways involved in inflammation and cancer specifically modulating protein kinases essential for cell proliferation In vitro SR-18292 demonstrates activity in the nanomolar to low micromolar range making it potent for biochemical assays Its typical applications include studies in various cell lines and animal models such as xenografts to assess anti-tumor efficacy and elucidate signaling mechanisms Additionally SR-18292 is utilized in drug screening programs to evaluate potential therapeutic interventions Experimental concentrations typically depend on the specific research design allowing for flexibility in research methodologies

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4,575

Apexbio Technology LLC GNE-781-5MG

GNE-781 (CAS No 1936422-33-1) is a promising small molecule under investigation in the biomedical research field for its potential therapeutic applications Originating from targeted drug discovery efforts this compound is known to interact with specific signaling pathways involved in disease progression although the exact mechanisms may still be under active exploration Its in vitro potency has been observed within the nanomolar to low micromolar range demonstrating significant activity in preliminary assays Commonly utilized in cell models and animal studies GNE-781 serves as a crucial component in drug screening pipelines to evaluate efficacy and safety profiles Experimental concentrations typically depend on the specific research design allowing for flexibility in various investigative contexts Its role in advancing our understanding of therapeutic targets makes it an invaluable tool in the drug development process

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Medchemexpress LLC (((9H-fluoren-9-yl)methoxy)carbonyl)-D-lysine | 110990-08-4 | MFCD04113545 | 99.5% | 368.43 g/mol | C21H24N2O4 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC BMS-707035 50 mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Boc-N-gamma-trityl-D-asparagin | 210529-01-4 | 98.6% | 474.55 g/mol | C28H30N2O5 | 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Gne-493 | 1033735-94-2 | MFCD18251526 | 99.8% | 372.44 g/mol | C17H20N6O2S | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Siais164018 hydrochloride | 00-00-0 | 98.1% | C43H49Cl2N10O7P | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Rabdosiin ((+)-Rabdosiin) | 263397-69-9 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC GUANOSINE-5 -TRIPHOS 500 mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More